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Is Childhood Adversity Related to a Higher Risk of Type 2 Diabetes in Early Adulthood?
A study of 1.2 million individuals found that individuals who experienced childhood adversity (such as maltreatment, physical and mental illness in family and poverty) are at higher risk of developing type 2 diabetes in early adulthood compared with individuals exposed to low adversity. Intervening upon proximal determinants of adversity may help reduce the number of T2D cases among young adults.
Patients With Atrial Fibrillation Have an Average of Five Additional Medical Conditions
Patients with atrial fibrillation have an average of 5 co-existing conditions including high BP, coronary artery disease, HF, obesity and CKD. The EHRA-PATHS consortium has created concise care pathways integrated in a software tool to check for whether a given comorbidity is present and to guide its further evaluation. This leads to better multidisciplinary management of patients with AF.
Artificial Intelligence may Soon Change How Physicians Approach Medical Care
Artificial intelligence may allow health care providers to combine large data sources to identify and calculate likely outcomes for individual patients which may prove helpful in diabetes care. The information is so detailed and you have access to so many patients in your database that you can make a good prediction of what’s going to happen next and diagnosis of diabetes complications.
Empagliflozin Improves Parameters of Left Atrial Function in Patients With Type 2 Diabetes
A post hoc analysis of the EMPA-Hemodynamics study which included 44 participants with type 2 diabetes and no AF/atrial flutter found that empagliflozin was associated with improved LA function after 3 months as assessed by a mean increase from 26.4% to 29% in LA strain reservoir and a mean increase from 10.9% to 12.5% in LA strain contraction phase values compared with placebo.
Lecanemab Helps Reduce Amyloid Markers in Patients with Early Alzheimer’s Disease
Lecanemab, a humanized IgG1 monoclonal antibody that binds to Aβ soluble protofibrils, was tested in persons with early Alzheimer’s disease. Lecanemab reduced markers of amyloid in early Alzheimer’s and resulted in moderately less decline on measures of cognition and function at 18 months but was associated with adverse events. Longer trials are warranted to determine its safety.
Physicians Shouldn't Take Hypertension Treatment Decisions Based Solely on In-Office BP Readings
A study found that BP readings taken in a physician’s office fluctuate from visit to visit, based on variations in timing, cuffs used, biological changes and context: Had the patient rushed to the appointment? Did they dine on a high sodium meal? Measuring BP in a standardized way helps, such as asking patients to sit and taking 3 consecutive measurements as 1st reading is always too high.
Frequently Eating French Fries may Increase the Risk for Anxiety and Depression
In multivariable analyses, fried food consumption increased the risk for anxiety by 12% and depression by 7%. Specifically, fried potato were associated with a 4% greater risk for anxiety and 2% risk for depression. The link were strongest in men and younger people. It was found that long-term exposure to acrylamidea dangerous fried food contaminant, elicited anxiety and depression behaviors.
Extracorporeal Cardiopulmonary Resuscitation (ECPR) Should Be Used in Selective Patients
ECPR may be considered a rescue therapy for select patients with cardiac arrest. These include some combination of variables: < 75 years, absence of severe comorbidities, cardiac arrest characteristics (eg, duration of resuscitation < 60 min, witnessed arrest, bystander CPR, initial shockable rhythm, signs of life during CPR), and physiologic parameters (lactate, end-tidal CO2, and pH).
30 Days Monitoring Detects More Arrhythmias in Hypertrophic Cardiomyopathy
Many patients with hypertrophic cardiomyopathy (HCM) develop atrial fibrillation or have non-sustained ventricular tachycardia (NSVT). TEMPO-HCM study showed that 30 days ECG monitoring using a continuous recording system in patients with HCM detects more arrhythmias VS standard 24-48 hours (65% vs. 11%). NSVT was detected in 62% of patients across 30 days VS 8% in the first 24 hours.
Novel Ablation Strategy Improves Freedom From Arrhythmias in Atrial Fibrillation Patients
An innovative 3 step ablation approach improves the recurrence of arrhythmias in patients with persistent atrial fibrillation than pulmonary vein isolation (PVI) alone (8 vs. 18 patients; p=0.026). The Marshall-Plan ablation strategy consists of 1) PVI; 2) ethanol infusion of the vein of Marshall; and 3) a linear ablation set to block the three main anatomical isthmuses to the pulmonary veins.
Bariatric Surgery can Treat Complications in People With Obesity and Diabetes
A study included 79 participants that completed the 2-year follow-up after undergoing bariatric surgery. All participants had class 2 or 3 obesity. After 2 years, the data showed an improvement in peripheral neuropathy, quality of life and pain among participant. Retinopathy and cardiac autonomic neuropathy were stable. There was an improvement metabolic risk factors, including weight reduction.
Prenatal Depression may Increase the Risk of Cardiovascular Disease After Childbirth
People with prenatal depression have high cardiovascular disease risk within 2 years of delivery.83% higher risk of ischemic heart disease; 60% higher risk of arrhythmia/cardiac arrest; 61% higher risk of cardiomyopathy; and 32% higher risk of new high blood pressure diagnosis. Additional pregnancy-related factors contributing to CVD may include chronic inflammation and stress-related hormones.
Is Metformin Use Associated With Incidence of Osteoarthritis (OA)?
A study included 41,874 patients with type 2 diabetes using metformin or a sulfonylurea. T1D/OA patients were excluded. It was found that the risk of developing OA was reduced by 24% for individuals treated with metformin than sulfonylurea, but there was no significant difference for risk of joint replacement. It suggests metformin may have a protective association against the development of OA.
Replacing Sugary Drinks With Coffee/Tea/Plain Water Lowers Mortality Risk in Adults With Diabetes
A recent study showed that the higher intake of sugar sweetened beverages (SSBs) is associated with higher all cause mortality and incidence of cardiovascular disease among adults with type 2 diabetes. Whereas intakes of coffee, tea, plain water, or low fat milk are associated with 18%, 16%, 16%, 12% reduced risk of all cause mortality respectively.